A03-2班 岩崎信太郎さんの研究成果が Nature Structural & Molecular Biologyに掲載されました。

A03-2班代表者の岩崎信太郎さんが責任著者を務める論文がNature Structural & Molecular Biologyに掲載されました。

Shichino Y, Yamaguchi T, Kashiwagi K, Mito M, Takahashi M, Ito T, Ingolia NT, Kuba K, Iwasaki S.
eIF4A1 enhances LARP1-mediated translational repression during mTORC1 inhibition.
Nat Struct Mol Biol. 2024 May 21.
doi: 10.1038/s41594-024-01321-7. PMID: 38773334. プレスリリース

eIF4A1 enhances LARP1-mediated translational repression during mTORC1 inhibition | Nature Structural & Molecular Biology

The authors revealed that the general translation factor eIF4A exerts a repressive effect on a subset of mRNAs by enhancing LARP1 and TOP mRNAs during mTORC1 i…